02206cam a2200253 a 450000500170000000800410001701000160005802000220007402000230009602000250011902000260014403500210017004000440019105000230023510000210025824500900027926000630036930000340043250400510046650513840051765000180190165000160191970000170193520230110150150.0120524s2009 enkm a001 0 eng  a2009-007437 a0471931659 (pbk.) a0471988200 (cloth) a9780471931652 (pbk.) a9780471988205 (cloth) a(OCoLC)311310165 aDLCcDLCdYDXCPdBWKUKdDEBBGdRVEdCDX 0aQP514.2b.N48 20091 aNewsholme, E. A.10aFunctional biochemistry in health and disease /cEric A. Newsholme and Tony R. Leech. aChichester, UK ;aHoboken, N.J. :bWiley-Blackwell,c2009. axvi, 543 p. :bill. ;c29 cm. aIncludes bibliographical references and index.0 aThe structural and biochemical hierarchy of a cell and a human -- Essential topics in dynamic biochemistry -- Energy : in the body, tissues and biochemical processes -- Enzymes : activities, properties, regulation and physiology -- Transport into the body : the gastrointestinal tract, digestion and absorption -- Transport into the cell: particles, molecules and ions -- Essential metabolism -- Carbohydrate metabolism -- Fat metabolism -- Amino acid and protein metabolism -- Oxidation of fuels and ATP generation: physiological and clinical importance -- Metabolism of ammonia and nucleic acids -- Synthesis of fatty acids, triacylglycerol, phospholipids and fatty messengers: the roles of polyunsaturated fatty acids -- Hormones : from action in the cell to function in the body -- Essential processes of life -- Physical activity : in non-athletes, athletes and patients -- Mental activity and mental illness -- Nutrition: biochemistry, physiology and pathology -- Starvation: metabolic changes, survival and death -- Defence against pathogens: barriers, enzymes and the immune system -- Survival after trauma: metabolic changes and response of the immune system -- Sexual reproduction -- Growth and death of cells and humans: the cell cycle, apoptosis and necrosis -- Serious diseases -- Cancer: genes, cachexia and death -- Atherosclerosis, hypertension and heart attack. 0aBiochemistry. 0aMetabolism.1 aLeech, A. R.